Deciduoid mesothelioma was first described in young females and in the peritoneum which led to the suggestion that deciduoid mesothelioma was a distinct subtype with specific clinical and pathologic features. Deciduoid mesothelioma is a rare variant of epithelial mesothelioma up to now only described in human pathology which bears remarkable cytomorphologic resemblance to the endometrium of pregnancy termed decidua.
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The term deciduoid reflects this subtypes histological resemblance to a cellular transformation that takes place during the early stages of pregnancy.
Deciduoid mesothelioma. Mesothelioma can develop in many different forms characterized by cell type and diagnosed through a biopsy. A case of peritoneal mesothelioma with deciduoid features in a 10 year old female dog is reported. Although this form of mesothelioma is diagnosed with a series of tests just as any other form of mesothelioma deciduoid mesothelioma resembles other diseases and even other tumors such as the pseudotumoral deciduosis which results in making an accurate diagnosis difficult.
Malignant deciduoid mesothelioma a rare phenotype of epithelioid mesothelioma arises more commonly from the peritoneum of young women but is also from the pleura of elderly people. Deciduoid mesothelioma is a rare cancer that unlike regular forms of mesothelioma which are detected in males is mostly detected in younger women. Deciduoid mesothelioma is the term used for an uncommon subtype of epithelioid mesothelioma that is characterized by the presence of cytomorphological features resembling decidua or decidualized.
Deciduoid mesothelioma is a rare variant of the epithelioid subtype and was previously thought to occur predominantly in the peritoneum of young women with no asbestos exposure3 4 however pleural cases are increasingly being described59. One form is deciduoid an epithelioid cell type that is very rare in mesothelioma. Trabecular micropapillary microcystic adenomatoid clear cell deciduoid small cell psammoma bodies might be present in any pattern be aware of reactive spindle cells that might mimic sarcomatoid component 2 5 show cytoplasmic mucin ultrastruct pathol 2006303.
In the current report the authors describe an unusual case of peritoneal malignant epithelioid mesothelioma with rare deciduoid phenotype demonstrated with 67 ga spectct. Most cases have been found in young women with peritoneal mesothelioma and like other types of mesothelioma are difficult to treat. Moreover where most mesothelioma cancers are caused by perpetual exposure to asbestos the bulk of experts agree there is no asbestos link to the deciduoid version.
Deciduoid mesothelioma is an unusual form of epithelial mesothelioma the most common of all mesothelioma cell types. Mesothelioma relevant other neoplasms that. Later reports however have shown that this type of mesothelioma may also occur in elderly people and in the pleura.
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